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Phenylpropaniods are organic compounds characterized by having an aromatic ring and a three-carbon propene tail. Polyketides are compounds characterized by having two or more carbonyl functional groups connected with a single carbon atom.
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3-Hydroxycoumarin is an inhibitor of tyrosinase and lipoxygenase. It exhibits photoprotective effects on sea urchin zygotes and embryos, and also demonstrates free radical scavenging activities.
Inhibits tyrosinase (IC50 for recombinant human tyrosinase of 26 μM) and lipoxygenase (IC50 for LOX of 9.5 μM).
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3-Carboxy-7-Hydroxycoumarin (CAS 779-27-1) is a coumarin-based fluorescent molecule It is characterized by blue fluorescence emission upon excitation with ultraviolet light Structurally it features a carboxyl group that enables conjugation via carbodiimide activation (e g EDAC-mediated formation of succinimidyl ester intermediates) allowing covalent attachment to amine-containing residues in proteins and nucleic acids Based on these properties 3-Carboxy-7-Hydroxycoumarin is commonly employed in biochemical research for fluorescent labeling including analysis of protein protein interactions nucleic acid visualization and biomolecule detection assays
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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7-Ethoxy-4-methylcoumarin is a coumarin derivative that serves as a substrate probe for mammalian cytochromes P450 1A1, 2B4, and 2B6. It is intended for research use only and not for sale to patients.
Functions as a substrate probe for mammalian cytochromes P450 1A1, 2B4, and 2B6.
Intended for research use only.
Appears as a white to off-white solid.
Ships at room temperature.
Recommended storage at 4°C, protected from light.
Soluble in DMSO at 50 mg/mL.
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7-Ethoxy-4-methylcoumarin is a coumarin derivative that can be used as a substrate probe for mammalian cytochromes P450 1A1, 2B4, and 2B6. It is for research use only.
Coumarin derivative
Substrate probe of mammalian cytochromes P450 1A1, 2B4 and 2B6
Solid appearance
White to off-white color
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AZP-531 is an analogue of unacylated ghrelin for research use, designed to improve glycaemic control and reduce weight. It shows survival effects on pancreatic β-cells and human pancreatic islets, and is highly stable in human plasma in vitro with no degradation after one day at 37°C.
Exhibits survival effects on pancreatic β-cells and human pancreatic islets.
Stable in human plasma in vitro at 37°C for one day.
Prevents high-fat diet-induced weight gain, proinflammatory effects, and prediabetic metabolic state in mice.
Stimulates mitochondrial function markers in brown adipose tissue.
Well-tolerated in clinical trials; improves glucose without increasing insulin.
Reduces mean body weight and HbA1c in clinical trials.
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